Research Efforts

The AC3 takes a multi-level approach to addressing racial disparities in cancer:

Our investigators work to fill in the "gaps" in current scientific knowledge through molecular epidemiology and behavioral studies

   For Researchers                            

   For Participants                            

We focus on resource building to support efforts toward the establishment of multi-center studies of cancer risk and outcomes through the development of standardized data collection instruments and protocols for biospecimen collection. 

Education and Training
We aim to promote diversity in research through capacity building efforts that involve training in research skills, grant writing and manuscript preparation workshops for AC3 research investigators and minority training programs for students. We increased awareness of the value of research and promote informed decision making in research participation by providing educational workshops that consist of presentations specifically designed to translate research results to the community.   

For Researchers    

The AC3 welcomes collaborations between consortium members as well as between AC3 members and non-members.

The AC3 research review committee will review and approve all proposals for collaborative projects that will be conducted under the umbrella of the AC3 (i.e. a study that would use information from AC3 research subjects, that would involve specimens, new data collection, or creation of new data in any investigation that is executed through collaboration within the AC3 network and infrastructure). Study proposals may be submitted by AC3 members (as an AC3 study) as well as interested non-members (as an ancillary study).

Definitions of an AC3 Study vs. an Ancillary Study

An AC3 study is one that is led by an AC3 member investigator and meets at least one of the following criteria:

  • A study that would be covered by specific aims of an AC3 Project (i.e. projects conducted and funded as AC3 multi-centered collaborations between at least two of the three AC3 networks, AC3-Africa, AC3-Caribbean and AC3-USA or within one of the three AC3 networks).
  • A study that would involve existing AC3 data only.

An Ancillary Study is one that is led by an AC3 non-member investigator and meets at least one of the following criteria:

  • A study that would use information from AC3 research subjects in an investigation that is not described as an AC3 multi-center project.
  • A study that would involve specimens, new data collection, or creation of new data (i.e. creating new derived variables) that are not included as part of the routine AC3 data set or data analyses.

The AC3-RERC will review and approve study proposals based on feasibility and will identify appropriate AC3 investigators if needed based on their research focus and expertise. The principles of this RERC policy are to provide research subject protection (ensure use of data does not exceed informed consent), coordinate efforts to avoid duplication of work, evaluate impact on the inventory of biological material and minimize barriers to publication of AC3 Studies.

 AC3-RERC Policy and Submission Guidelines

Please submit your proposals to Delroy M. Louden, PhD at 


For Participants  

Through our community engagement efforts we have developed a successful model for population-based health disparities research studies. We provide the community not only with information about the importance of incorporating cancer prevention practice and screening into their lifestyle but we also provide community members with a better understanding of the importance of cancer disparities research and the value of participating in research studies. This approach over the years has led to an overwhelming acceptance, thus providing us with the ability to successfully recruit study participants of African Ancestry. This model involving community engagement and research recruitment has been successfully adapted for a number of studies:

Cancer Prevention Project of Philadelphia (CAP3)

PI: Camille Ragin, PhD, MPH

Status: Open for enrollment

The CAP3 study is research registry of cancer-free participants and serves as a pipeline project for our population-based molecular epidemiology research studies. To date there are more than 750 (US-born, Caribbean-born and African-born) participants enrolled and recruitment is ongoing.

To learn more please call Dr. Camille Ragin at 215-728-1148 or email